Assay Detail
Binding
CHEMBL3598826
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of His6-tagged Mycobacterium tuberculosis Rv3588c expressed in Escherichia coli BL21-AI cells by stopped flow CO2 hydration assay based Michaelis-Menten analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mycobacterium tuberculosis |
| Cell Type | BL21-AI |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Non-classical -carbonic anhydrase inhibitors-towards novel anti-mycobacterials
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.89 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1644028 | THIOCYANATE SODIUM | -1.0 | 1 | 5.10 |
| CHEMBL3597014 | — | — | 1 | 5.00 |
| CHEMBL2047174 | IANTHELLIFORMISAMINE C | — | 1 | 4.80 |
| CHEMBL396652 | SPERMATINAMINE | — | 1 | 4.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1644028 | THIOCYANATE SODIUM | Ki | = | 8000.0 | nM | 5.10 |
| CHEMBL3597014 | — | Ki | = | 10000.0 | nM | 5.00 |
| CHEMBL2047174 | IANTHELLIFORMISAMINE C | Ki | = | 16000.0 | nM | 4.80 |
| CHEMBL396652 | SPERMATINAMINE | Ki | = | 23000.0 | nM | 4.64 |