Assay Detail
Functional
CHEMBL3598853
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Antiproliferative activity against human SK-UT-1B cells assessed as cell growth inhibition after 48 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Skut1B |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phospholipid derivatives of cladribine and fludarabine: synthesis and biological properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.61 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1619 | CLADRIBINE | 4.0 | 1 | 6.00 |
| CHEMBL1096882 | FLUDARABINE PHOSPHATE | 4.0 | 1 | 5.22 |
| CHEMBL3597228 | — | — | 1 | - |
| CHEMBL3597227 | — | — | 1 | - |
| CHEMBL3597226 | — | — | 1 | - |
| CHEMBL3597225 | — | — | 1 | - |
| CHEMBL3597147 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1619 | CLADRIBINE | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL1096882 | FLUDARABINE PHOSPHATE | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL3597228 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3597227 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3597226 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3597225 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3597147 | — | IC50 | > | 100000.0 | nM | - |