Assay Detail
Binding
CHEMBL3598921
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human HDAC10
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Evaluation of histone deacetylase inhibitors (HDACi) as therapeutic leads for human African trypanosomiasis (HAT).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.00 | 10.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2105763 | QUISINOSTAT | 2.0 | 1 | 10.30 |
| CHEMBL1851943 | PRACINOSTAT | 3.0 | 1 | 7.64 |
| CHEMBL2103863 | ABEXINOSTAT | 3.0 | 1 | 7.62 |
| CHEMBL356769 | TUBACIN | — | 1 | 6.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2105763 | QUISINOSTAT | Ki | = | 0.05 | nM | 10.30 |
| CHEMBL1851943 | PRACINOSTAT | Ki | = | 23.0 | nM | 7.64 |
| CHEMBL2103863 | ABEXINOSTAT | Ki | = | 24.0 | nM | 7.62 |
| CHEMBL356769 | TUBACIN | Ki | = | 373.7 | nM | 6.43 |