Assay Detail
Binding
CHEMBL3599575
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Inhibition of influenza virus neuraminidase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | unidentified adenovirus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Conformational analysis of peramivir reveals critical differences between free and enzyme-bound states
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.50 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL139367 | PERAMIVIR ANHYDROUS | 4.0 | 1 | 10.00 |
| CHEMBL222813 | ZANAMIVIR | 4.0 | 1 | 9.00 |
| CHEMBL674 | OSELTAMIVIR CARBOXYLATE | -1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL139367 | PERAMIVIR ANHYDROUS | IC50 | = | 0.1 | nM | 10.00 |
| CHEMBL222813 | ZANAMIVIR | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL674 | OSELTAMIVIR CARBOXYLATE | IC50 | = | 1.0 | nM | - |