Assay Detail

CHEMBL3599768

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Functional

Cytotoxicity against human NCI/ADR cells

ChEMBL ↗

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Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Open DB target context

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Primary target NON-PROTEIN TARGET

CHEMBL3879801

Anchored from Assay target.

Protein identity NON-PROTEIN TARGET

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	NCI/ADR
Confidence	1 — Organism
Curated By	Autocuration

Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Type	NON-MOLECULAR

Publication

Progress Toward the Development of Noscapine and Derivatives as Anticancer Agents.

DeBono A, Capuano B, Scammells PJ.
J Med Chem (2015) 58 : 5699 -5727
PubMed 25811651 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	9.44	9.44

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL107	COLCHICINE	4.0	1	9.44

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL107	COLCHICINE	IC50	=	0.36	nM	9.44