Assay Detail
Functional
CHEMBL3603298
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Cytotoxicity against human MV-3 cells after 72 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MV-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Scaffold Diversity Inspired by the Natural Product Evodiamine: Discovery of Highly Potent and Multitargeting Antitumor Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.11 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3600931 | — | — | 1 | 6.85 |
| CHEMBL3600388 | — | — | 1 | 5.96 |
| CHEMBL3600612 | — | — | 1 | 5.92 |
| CHEMBL3600930 | — | — | 1 | 5.92 |
| CHEMBL3600929 | — | — | 1 | 5.89 |
| CHEMBL65 | CAMPTOTHECIN | -1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3600931 | — | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL3600388 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL3600612 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL3600930 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL3600929 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL65 | CAMPTOTHECIN | IC50 | < | 3.0 | nM | - |