Assay Detail
Functional
CHEMBL3603300
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human Bel7404 cells after 72 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | BEL-7404 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Scaffold Diversity Inspired by the Natural Product Evodiamine: Discovery of Highly Potent and Multitargeting Antitumor Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.04 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3600612 | — | — | 1 | 7.22 |
| CHEMBL65 | CAMPTOTHECIN | -1.0 | 1 | 6.85 |
| CHEMBL3600388 | — | — | 1 | - |
| CHEMBL3600929 | — | — | 1 | - |
| CHEMBL3600930 | — | — | 1 | - |
| CHEMBL3600931 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3600612 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL65 | CAMPTOTHECIN | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL3600388 | — | IC50 | < | 3.0 | nM | - |
| CHEMBL3600929 | — | IC50 | < | 3.0 | nM | - |
| CHEMBL3600930 | — | IC50 | < | 3.0 | nM | - |
| CHEMBL3600931 | — | IC50 | < | 3.0 | nM | - |