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Assay Detail

CHEMBL3603312

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of BLK (unknown origin) by Z'-Lyte assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Tyrosine-protein kinase Blk (CHEMBL2250)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Development of Selective Covalent Janus Kinase 3 Inhibitors.
Tan L, Akahane K, McNally R, Reyskens KM, Ficarro SB, Liu S, Herter-Sprie GS, Koyama S, Pattison MJ, Labella K, Johannessen L, Akbay EA, Wong KK, Frank DA, Marto JA, Look TA, Arthur JS, Eck MJ, Gray NS.
J Med Chem (2015) 58 : 6589 -6606
PubMed 26258521 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.80 6.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3601223 1 6.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3601223 IC50 = 157.0 nM 6.80