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Assay Detail

CHEMBL3606221

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against HDF after 24 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Cell Type HDF
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile.
Prati F, Bergamini C, Molina MT, Falchi F, Cavalli A, Kaiser M, Brun R, Fato R, Bolognesi ML.
J Med Chem (2015) 58 : 6422 -6434
PubMed 26237241 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 4.88 5.01

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL256155 1 5.01
CHEMBL3604082 1 4.92
CHEMBL3604105 1 4.82
CHEMBL3604098 1 4.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL256155 IC50 = 9840.0 nM 5.01
CHEMBL3604082 IC50 = 11900.0 nM 4.92
CHEMBL3604105 IC50 = 15010.0 nM 4.82
CHEMBL3604098 IC50 = 17100.0 nM 4.77