Assay Detail
ADMET
CHEMBL3606614
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Cytotoxicity against mouse C3H10T1/2 cells after 24 hrs by FMCA
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | C3H 10T1/2 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Hedgehog inhibitors from Withania somnifera.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.13 | 5.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2047410 | — | — | 1 | 5.39 |
| CHEMBL517080 | WITHAFERIN A | 1.0 | 1 | 5.31 |
| CHEMBL469945 | — | — | 1 | 4.68 |
| CHEMBL3234469 | — | — | 1 | - |
| CHEMBL1934585 | — | — | 1 | - |
| CHEMBL1934583 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2047410 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL517080 | WITHAFERIN A | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL469945 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL3234469 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1934585 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1934583 | — | IC50 | > | 25000.0 | nM | - |