Assay Detail
Binding
CHEMBL3606653
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of human CDK2/cyclinA using PKTPKKAKKL as substrate in presence of ATP
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
Cyclin-dependent kinase 2/cyclin A (CHEMBL2094128) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
Cyclin dependent kinase (CDK) inhibitors as anticancer drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.56 | 4.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL66953 | PURPUROGALLIN | — | 1 | 4.77 |
| CHEMBL3604459 | — | — | 1 | 4.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL66953 | PURPUROGALLIN | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL3604459 | — | IC50 | = | 45000.0 | nM | 4.35 |