Assay Detail
Functional
CHEMBL3607081
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Rift Valley fever virus infected in African green monkey Vero 76 cells after 3 days by neutral red dye-based plaque reduction assay
9
Total Activities
9
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rift Valley fever virus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
2- and 3-Fluoro-3-deazaneplanocins, 2-fluoro-3-deazaaristeromycins, and 3-methyl-3-deazaneplanocin: Synthesis and antiviral properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 5 | - | - |
| IC50 | 4 | 5.17 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3604362 | — | — | 1 | 5.89 |
| CHEMBL3604361 | — | — | 1 | 5.19 |
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 4.43 |
| CHEMBL3603846 | — | — | 1 | - |
| CHEMBL3604363 | — | — | 1 | - |
| CHEMBL3604364 | — | — | 1 | - |
| CHEMBL3604365 | — | — | 1 | - |
| CHEMBL3604366 | — | — | 1 | - |
| CHEMBL3604367 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3604362 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL3604361 | — | IC50 | = | 6400.0 | nM | 5.19 |
| CHEMBL1643 | RIBAVIRIN | IC50 | = | 37300.0 | nM | 4.43 |
| CHEMBL3603846 | — | IC50 | > | 36000.0 | nM | - |
| CHEMBL3604363 | — | Activity | - | — | - | |
| CHEMBL3604364 | — | Activity | - | — | - | |
| CHEMBL3604365 | — | Activity | - | — | - | |
| CHEMBL3604366 | — | Activity | - | — | - | |
| CHEMBL3604367 | — | Activity | - | — | - |