Assay Detail
Functional
CHEMBL3607143
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Cytotoxicity against human KG1a cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KG-1a |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Syntheses and Biological Evaluation of Costunolide, Parthenolide, and Their Fluorinated Analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.48 | 5.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3603951 | — | — | 1 | 5.75 |
| CHEMBL3603952 | — | — | 1 | 5.70 |
| CHEMBL4298697 | — | — | 1 | 5.64 |
| CHEMBL3603949 | — | — | 1 | 5.54 |
| CHEMBL86416 | COSTUNOLIDE | — | 1 | 5.39 |
| CHEMBL3603953 | — | — | 1 | 5.29 |
| CHEMBL3603950 | — | — | 1 | 5.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3603951 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL3603952 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL4298697 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL3603949 | — | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL86416 | COSTUNOLIDE | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL3603953 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL3603950 | — | IC50 | = | 8600.0 | nM | 5.07 |