Assay Detail
ADMET
CHEMBL3608068
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CYP1A2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.67 | 4.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3604174 | — | — | 1 | 4.67 |
| CHEMBL3604137 | — | — | 1 | - |
| CHEMBL3604140 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3604174 | — | IC50 | = | 21600.0 | nM | 4.67 |
| CHEMBL3604137 | — | IC50 | - | — | - | |
| CHEMBL3604140 | — | IC50 | - | — | - |