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Assay Detail

CHEMBL3610066

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Human respiratory syncytial virus
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human respiratory syncytial virus
Confidence 1 — Organism
Curated By Autocuration

Target

Human orthopneumovirus (CHEMBL613127)
Type ORGANISM
Organism Human orthopneumovirus

Publication

Potential Treatment for the Respiratory Syncytial Virus Infections (HRSV).
Abdel-Magid AF.
ACS Med Chem Lett (2015) 6 : 734 -735
PubMed 26191357 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 5 5.49 6.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3608439 1 6.24
CHEMBL3608438 1 6.00
CHEMBL3608435 1 5.14
CHEMBL3608679 1 5.04
CHEMBL3608436 1 5.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3608439 EC50 = 570.0 nM 6.24
CHEMBL3608438 EC50 = 1000.0 nM 6.00
CHEMBL3608435 EC50 = 7300.0 nM 5.14
CHEMBL3608679 EC50 = 9200.0 nM 5.04
CHEMBL3608436 EC50 = 9600.0 nM 5.02