Assay Detail

CHEMBL3611403

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Functional

Antiviral activity against HIV1 TLAV

ChEMBL ↗

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Target

Human immunodeficiency virus 1 (CHEMBL378) ↗

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Human immunodeficiency virus 1 (CHEMBL378) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Human immunodeficiency virus 1

CHEMBL378

Anchored from Assay target.

Protein identity Human immunodeficiency virus 1

Disease frame Disease evidence pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Human immunodeficiency virus 1
Confidence	1 — Organism
Curated By	Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378) ↗

Type	ORGANISM
Organism	Human immunodeficiency virus 1

Publication

Pyrroloaryls and pyrroloheteroaryls: Inhibitors of the HIV fusion/attachment, reverse transcriptase and integrase.

Patel RV, Park SW.
Bioorg Med Chem (2015) 23 : 5247 -5263
PubMed 26116177 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	2	6.07	6.07

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL135339	—	—	1	6.07
CHEMBL336293	—	—	1	6.07

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL135339	—	EC50	=	850.0	nM	6.07
CHEMBL336293	—	EC50	=	850.0	nM	6.07