Assay Detail
Binding
CHEMBL3619487
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to ERCC1-XPF (unknown origin) by SPR assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
DNA excision repair protein ERCC-1/DNA repair endonuclease XPF (CHEMBL3883316) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
N-Hydroxyimides and hydroxypyrimidinones as inhibitors of the DNA repair complex ERCC1-XPF.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 5.40 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3617205 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3617205 | — | Kd | = | 4000.0 | nM | 5.40 |