Assay Detail
Binding
CHEMBL3626078
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of MDMX/p53 (unknown origin) interaction
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Tumour suppressor protein p53/Mdm4 (CHEMBL2221344) ↗| Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
Publication
Rational design of proteinprotein interaction inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 4.82 | 4.82 |
| Ki | 1 | 8.17 | 8.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3621947 | — | — | 1 | 8.17 |
| CHEMBL1478 | LITHOCHOLIC ACID | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3621947 | — | Ki | = | 6.8 | nM | 8.17 |
| CHEMBL1478 | LITHOCHOLIC ACID | Kd | = | 15000.0 | nM | 4.82 |