Assay Detail
Functional
CHEMBL3626196
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Cytotoxicity against human Glioma cells (HF2476) after 72 hrs by CelltiterGlo assay
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Glioma |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 9.15 | 9.15 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1879463 | DACTOLISIB | 3.0 | 1 | 9.15 |
| CHEMBL3622533 | FIMEPINOSTAT | 2.0 | 1 | 9.15 |
| CHEMBL325041 | BORTEZOMIB | 3.0 | 1 | 9.15 |
| CHEMBL1801204 | AZD-8055 | 1.0 | 1 | 9.15 |
| CHEMBL443684 | NAVITOCLAX | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1879463 | DACTOLISIB | EC50 | = | 0.7 | nM | 9.15 |
| CHEMBL3622533 | FIMEPINOSTAT | EC50 | = | 0.7 | nM | 9.15 |
| CHEMBL325041 | BORTEZOMIB | EC50 | = | 0.7 | nM | 9.15 |
| CHEMBL1801204 | AZD-8055 | EC50 | = | 0.7 | nM | 9.15 |
| CHEMBL443684 | NAVITOCLAX | Activity | - | — | - |