Assay Detail
Functional
CHEMBL3626342
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Cytotoxicity against human Calu6 cells assessed as cell viability incubated for 48 to 72 hrs by MTS method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Calu-6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.30 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL378900 | — | — | 1 | 5.30 |
| CHEMBL3621615 | — | — | 1 | - |
| CHEMBL1605826 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL378900 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL3621615 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1605826 | — | IC50 | > | 100000.0 | nM | - |