Assay Detail
Functional
CHEMBL3626466
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Cytotoxicity against human QGY7701 cells assessed as growth inhibition incubated for 72 hrs by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | QGY7701 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, cytotoxicity and inhibition of NO production of ivangustin enantiomer analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.28 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.77 |
| CHEMBL3622082 | — | — | 1 | 5.45 |
| CHEMBL3621396 | — | — | 1 | 5.31 |
| CHEMBL3622083 | — | — | 1 | 5.26 |
| CHEMBL3622080 | — | — | 1 | 5.21 |
| CHEMBL3622079 | — | — | 1 | 5.11 |
| CHEMBL3622084 | — | — | 1 | 5.07 |
| CHEMBL3622078 | — | — | 1 | 5.06 |
| CHEMBL3622081 | — | — | 1 | 4.86 |
| CHEMBL3622085 | — | — | 1 | 4.65 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL3622082 | — | IC50 | = | 3550.0 | nM | 5.45 |
| CHEMBL3621396 | — | IC50 | = | 4880.0 | nM | 5.31 |
| CHEMBL3622083 | — | IC50 | = | 5550.0 | nM | 5.26 |
| CHEMBL3622080 | — | IC50 | = | 6160.0 | nM | 5.21 |
| CHEMBL3622079 | — | IC50 | = | 7750.0 | nM | 5.11 |
| CHEMBL3622084 | — | IC50 | = | 8580.0 | nM | 5.07 |
| CHEMBL3622078 | — | IC50 | = | 8700.0 | nM | 5.06 |
| CHEMBL3622081 | — | IC50 | = | 13700.0 | nM | 4.86 |
| CHEMBL3622085 | — | IC50 | = | 22410.0 | nM | 4.65 |