Assay Detail
Binding
CHEMBL3627232
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of alpha-thrombin (unknown origin) using Ac-ATPRpNA substrate by spectrophotometry method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Improving the Selectivity of Engineered Protease Inhibitors: Optimizing the P2 Prime Residue Using a Versatile Cyclic Peptide Library.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.55 | 6.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3623793 | — | — | 1 | 6.67 |
| CHEMBL3623792 | — | — | 1 | 6.42 |
| CHEMBL3623789 | — | — | 1 | - |
| CHEMBL3623788 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3623793 | — | Ki | = | 214.0 | nM | 6.67 |
| CHEMBL3623792 | — | Ki | = | 381.0 | nM | 6.42 |
| CHEMBL3623789 | — | Ki | > | 50000.0 | nM | - |
| CHEMBL3623788 | — | Ki | > | 50000.0 | nM | - |