Assay Detail
Binding
CHEMBL3631057
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Inhibition of c-MET (unknown origin) by radiometric protein kinase assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of di-aryl urea derivatives as c-Kit inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.64 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2018882 | — | — | 1 | 5.64 |
| CHEMBL3628811 | — | — | 1 | - |
| CHEMBL3628808 | — | — | 1 | - |
| CHEMBL3628807 | — | — | 1 | - |
| CHEMBL3628799 | — | — | 1 | - |
| CHEMBL3628798 | — | — | 1 | - |
| CHEMBL3628797 | — | — | 1 | - |
| CHEMBL3628796 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2018882 | — | IC50 | = | 2310.0 | nM | 5.64 |
| CHEMBL3628811 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3628808 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3628807 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3628799 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3628798 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3628797 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3628796 | — | IC50 | - | — | - |