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Assay Detail

CHEMBL3632075

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HL60 cells assessed as growth inhibition after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HL-60
Confidence 1 — Organism
Curated By Autocuration

Target

HL-60 (CHEMBL383)
Type CELL-LINE
Organism Homo sapiens

Publication

Identification of a molecular target of kurahyne, an apoptosis-inducing lipopeptide from marine cyanobacterial assemblages.
Iwasaki A, Ohno O, Katsuyama S, Morita M, Sasazawa Y, Dan S, Simizu S, Yamori T, Suenaga K.
Bioorg Med Chem Lett (2015) 25 : 5295 -5298
PubMed 26428873 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.82 5.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3628709 1 5.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3628709 IC50 = 1500.0 nM 5.82