Assay Detail
Binding
CHEMBL3635653
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of GST-tagged PTP1B (unknown origin) by plate reader analysis using DiFMUP as substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 1 (CHEMBL335) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification of Bidentate Salicylic Acid Inhibitors of PTP1B.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.50 | 5.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3632912 | — | — | 1 | 5.74 |
| CHEMBL1829864 | — | — | 1 | 5.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3632912 | — | Ki | = | 1830.0 | nM | 5.74 |
| CHEMBL1829864 | — | Ki | = | 5660.0 | nM | 5.25 |