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Assay Detail

CHEMBL3636746

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Functional
Cytotoxicity against human MM1S cells after 72 hrs by CellTiter-Glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MM1.S
Confidence 1 — Organism
Curated By Autocuration

Publication

Discovery of 3,5-substituted 6-azaindazoles as potent pan-Pim inhibitors.
Hu H, Wang X, Chan GK, Chang JH, Do S, Drummond J, Ebens A, Lee W, Ly J, Lyssikatos JP, Murray J, Moffat JG, Chao Q, Tsui V, Wallweber H, Kolesnikov A.
Bioorg Med Chem Lett (2015) 25 : 5258 -5264
PubMed 26459208 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.19 6.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3634761 1 6.19

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3634761 IC50 = 640.0 nM 6.19