Assay Detail
Functional
CHEMBL3637087
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimigratory activity in mouse B16F10 cells after 24 hrs by vitronectin-coated boyden chamber assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B16-F10 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
α-Halogenated oxaphosphinanes: Synthesis, unexpected reactions and evaluation as inhibitors of cancer cell proliferation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 7.30 | 7.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3633920 | — | — | 1 | 7.68 |
| CHEMBL3633925 | — | — | 1 | 7.47 |
| CHEMBL3633919 | — | — | 1 | 7.46 |
| CHEMBL3633924 | — | — | 1 | 7.40 |
| CHEMBL3633918 | — | — | 1 | 7.36 |
| CHEMBL3633921 | — | — | 1 | 7.30 |
| CHEMBL3633922 | — | — | 1 | 6.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3633920 | — | Ki | = | 21.0 | nM | 7.68 |
| CHEMBL3633925 | — | Ki | = | 34.0 | nM | 7.47 |
| CHEMBL3633919 | — | Ki | = | 35.0 | nM | 7.46 |
| CHEMBL3633924 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL3633918 | — | Ki | = | 44.0 | nM | 7.36 |
| CHEMBL3633921 | — | Ki | = | 50.0 | nM | 7.30 |
| CHEMBL3633922 | — | Ki | = | 380.0 | nM | 6.42 |