Assay Detail
Binding
CHEMBL3707766
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Inhibition Assay: Inhibition assay using P450 CYP enzymes.
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
17Beta-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of hormone-related diseases
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.66 | 6.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1650658 | — | — | 1 | 6.17 |
| CHEMBL3645217 | — | — | 1 | 6.06 |
| CHEMBL1650646 | — | — | 1 | 5.92 |
| CHEMBL3645215 | — | — | 1 | 5.12 |
| CHEMBL3645225 | — | — | 1 | 5.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1650658 | — | IC50 | = | 680.0 | nM | 6.17 |
| CHEMBL3645217 | — | IC50 | = | 880.0 | nM | 6.06 |
| CHEMBL1650646 | — | IC50 | = | 1210.0 | nM | 5.92 |
| CHEMBL3645215 | — | IC50 | = | 7540.0 | nM | 5.12 |
| CHEMBL3645225 | — | IC50 | = | 8830.0 | nM | 5.05 |