Assay Detail
Binding
CHEMBL3707912
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Inhibition Assay: In vitro inhibition assay using various enzyme.
6
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Compound useful for the treatment of degenerative and inflammatory diseases
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.54 | 6.83 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3301607 | FILGOTINIB | 4.0 | 4 | 6.83 |
| CHEMBL3360356 | — | — | 1 | 6.71 |
| CHEMBL3360353 | — | — | 1 | 5.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3301607 | FILGOTINIB | IC50 | = | 149.35 | nM | 6.83 |
| CHEMBL3301607 | FILGOTINIB | IC50 | = | 187.3 | nM | 6.73 |
| CHEMBL3301607 | FILGOTINIB | IC50 | = | 189.3 | nM | 6.72 |
| CHEMBL3360356 | — | IC50 | = | 194.6 | nM | 6.71 |
| CHEMBL3301607 | FILGOTINIB | IC50 | = | 194.7 | nM | 6.71 |
| CHEMBL3360353 | — | IC50 | = | 2843.0 | nM | 5.55 |