Assay Detail
Binding
CHEMBL3720899
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human T1R2/T1R3 expressed in HEK293T cells co-expressing Galpha15/i1 assessed as reduction in 1 mM D-tryptophan saccharin-induced response
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK-293T |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.70 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3715108 | LACTISOLE SODIUM | 1.0 | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3715108 | LACTISOLE SODIUM | IC50 | = | 19900.0 | nM | 4.70 |