Assay Detail
Functional
CHEMBL3721025
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Cytotoxicity against human HCT116 cells by fluorescent Calcein-AM assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Tautomycetin and Tautomycetin analog biosynthesis
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.91 | 5.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1366322 | — | — | 1 | 5.17 |
| CHEMBL3719114 | — | — | 1 | 4.80 |
| CHEMBL3715079 | — | — | 1 | 4.75 |
| CHEMBL3716789 | — | — | 1 | - |
| CHEMBL3718369 | — | — | 1 | - |
| CHEMBL3718785 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1366322 | — | IC50 | = | 6800.0 | nM | 5.17 |
| CHEMBL3719114 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL3715079 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL3716789 | — | IC50 | - | — | - | |
| CHEMBL3718369 | — | IC50 | - | — | - | |
| CHEMBL3718785 | — | IC50 | - | — | - |