Assay Detail
Binding
CHEMBL3734242
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Nox2 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Tetrahydroisoquinolines as selective nadph oxidase 2 inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.52 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3347550 | — | — | 1 | 7.52 |
| CHEMBL3733336 | — | — | 1 | 7.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3347550 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL3733336 | — | IC50 | = | 30.0 | nM | 7.52 |