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Assay Detail

CHEMBL3734283

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human GRK2 after 90 to 120 mins by Kinase-Glo assay
ChEMBL ↗
97
Total Activities
97
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Beta-adrenergic receptor kinase 1 (CHEMBL4079) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Hydrazide compounds
(2007)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 97 6.67 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3728531 — — 1 8.00
CHEMBL3732726 — — 1 8.00
CHEMBL3732018 — — 1 8.00
CHEMBL3731835 — — 1 8.00
CHEMBL3729453 — — 1 8.00
CHEMBL3732468 — — 1 8.00
CHEMBL3728772 — — 1 8.00
CHEMBL3729519 — — 1 7.00
CHEMBL3728959 — — 1 7.00
CHEMBL3733136 — — 1 7.00
CHEMBL3730555 — — 1 7.00
CHEMBL3732073 — — 1 7.00
CHEMBL3731262 — — 1 7.00
CHEMBL3732155 — — 1 7.00
CHEMBL3729597 — — 1 7.00
CHEMBL3727632 — — 1 7.00
CHEMBL3729044 — — 1 7.00
CHEMBL3729970 — — 1 7.00
CHEMBL3727506 — — 1 7.00
CHEMBL3729682 — — 1 7.00
CHEMBL3728684 — — 1 7.00
CHEMBL3731472 — — 1 7.00
CHEMBL3728445 — — 1 7.00
CHEMBL3731114 — — 1 7.00
CHEMBL3730586 — — 1 7.00
CHEMBL3729412 — — 1 7.00
CHEMBL3728261 — — 1 7.00
CHEMBL3729247 — — 1 7.00
CHEMBL3730425 — — 1 7.00
CHEMBL3727728 — — 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3728531 — Ki = 10.0 nM 8.00
CHEMBL3732726 — Ki = 10.0 nM 8.00
CHEMBL3732018 — Ki = 10.0 nM 8.00
CHEMBL3731835 — Ki = 10.0 nM 8.00
CHEMBL3729453 — Ki = 10.0 nM 8.00
CHEMBL3732468 — Ki = 10.0 nM 8.00
CHEMBL3728772 — Ki = 10.0 nM 8.00
CHEMBL3732073 — Ki = 100.0 nM 7.00
CHEMBL3729597 — Ki = 100.0 nM 7.00
CHEMBL3731262 — Ki = 100.0 nM 7.00
CHEMBL3732155 — Ki = 100.0 nM 7.00
CHEMBL3727632 — Ki = 100.0 nM 7.00
CHEMBL3729044 — Ki = 100.0 nM 7.00
CHEMBL3729970 — Ki = 100.0 nM 7.00
CHEMBL3728959 — Ki = 100.0 nM 7.00
CHEMBL3728346 — Ki = 100.0 nM 7.00
CHEMBL3728662 — Ki = 100.0 nM 7.00
CHEMBL3730250 — Ki = 100.0 nM 7.00
CHEMBL3730062 — Ki = 100.0 nM 7.00
CHEMBL3730343 — Ki = 100.0 nM 7.00
CHEMBL3727997 — Ki = 100.0 nM 7.00
CHEMBL3733136 — Ki = 100.0 nM 7.00
CHEMBL3727728 — Ki = 100.0 nM 7.00
CHEMBL3730425 — Ki = 100.0 nM 7.00
CHEMBL3729247 — Ki = 100.0 nM 7.00
CHEMBL3728261 — Ki = 100.0 nM 7.00
CHEMBL3729412 — Ki = 100.0 nM 7.00
CHEMBL3730586 — Ki = 100.0 nM 7.00
CHEMBL3731114 — Ki = 100.0 nM 7.00
CHEMBL3731472 — Ki = 100.0 nM 7.00
CHEMBL3728684 — Ki = 100.0 nM 7.00
CHEMBL3729682 — Ki = 100.0 nM 7.00
CHEMBL3727506 — Ki = 100.0 nM 7.00
CHEMBL3729519 — Ki = 100.0 nM 7.00
CHEMBL3730555 — Ki = 100.0 nM 7.00
CHEMBL3728445 — Ki = 100.0 nM 7.00
CHEMBL3731647 — Ki = 1000.0 nM 6.00
CHEMBL3731537 — Ki = 1000.0 nM 6.00
CHEMBL3727573 — Ki = 1000.0 nM 6.00
CHEMBL3730286 — Ki = 1000.0 nM 6.00
CHEMBL3730611 — Ki = 1000.0 nM 6.00
CHEMBL3727962 — Ki = 1000.0 nM 6.00
CHEMBL3729359 — Ki = 1000.0 nM 6.00
CHEMBL3727996 — Ki = 1000.0 nM 6.00
CHEMBL3733170 — Ki = 1000.0 nM 6.00
CHEMBL3730458 — Ki = 1000.0 nM 6.00
CHEMBL3729052 — Ki = 1000.0 nM 6.00
CHEMBL3728097 — Ki = 1000.0 nM 6.00
CHEMBL3730299 — Ki = 1000.0 nM 6.00
CHEMBL3731839 — Ki = 1000.0 nM 6.00