Assay Detail
Binding
CHEMBL3734289
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GRK2 in human U2OS cells assessed as inhibition of isoproterenol-induced translocation of arrestin-GFP to beta 2 adrenergic receptor preincubated for 60 mins by Transfluor assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | U2OS |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Hydrazide compounds
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.40 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3729453 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3729453 | — | IC50 | = | 4000.0 | nM | 5.40 |