Assay Detail
Binding
CHEMBL3737251
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Agonist activity at goat NK3 receptor expressed in CHO cells assessed as calcium influx relative to 100 nM senktide
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Capra hircus |
| Cell Type | CHO |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structureactivity relationship study on senktide for development of novel potent neurokinin-3 receptor selective agonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 10.82 | 10.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3734811 | — | — | 1 | 10.92 |
| CHEMBL106124 | SENKTIDE | — | 1 | 10.72 |
| CHEMBL3736361 | — | — | 1 | - |
| CHEMBL3736089 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3734811 | — | EC50 | = | 0.012 | nM | 10.92 |
| CHEMBL106124 | SENKTIDE | EC50 | = | 0.019 | nM | 10.72 |
| CHEMBL3736361 | — | EC50 | = | 0.0094 | nM | - |
| CHEMBL3736089 | — | EC50 | = | 0.0093 | nM | - |