Assay Detail
Binding
CHEMBL3739090
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Inhibition of mouse plasmin after 15 mins using H-D-Ile-Pro-Arg-p-nitroanilide as substrate
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design of Specific Serine Protease Inhibitors Based on a Versatile Peptide Scaffold: Conversion of a Urokinase Inhibitor to a Plasma Kallikrein Inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 5.48 | 5.53 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3735513 | — | — | 1 | 5.53 |
| CHEMBL3735217 | — | — | 1 | 5.47 |
| CHEMBL3735263 | — | — | 1 | 5.43 |
| CHEMBL3734777 | — | — | 1 | - |
| CHEMBL3735080 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3735513 | — | Ki | = | 2970.0 | nM | 5.53 |
| CHEMBL3735217 | — | Ki | = | 3420.0 | nM | 5.47 |
| CHEMBL3735263 | — | Ki | = | 3670.0 | nM | 5.43 |
| CHEMBL3734777 | — | Ki | > | 1000000.0 | nM | - |
| CHEMBL3735080 | — | Ki | > | 1000000.0 | nM | - |