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Assay Detail

CHEMBL3743960

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Functional
Antiviral activity against EV71
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Enterovirus A71
Confidence 1 — Organism
Curated By Autocuration

Target

Enterovirus A71 (CHEMBL612436)
Type ORGANISM
Organism Enterovirus A71

Publication

Identification, synthesis and pharmacological evaluation of novel anti-EV71 agents via cyclophilin A inhibition.
Yan W, Qing J, Mei H, Nong J, Huang J, Zhu J, Jiang H, Liu L, Zhang L, Li J.
Bioorg Med Chem Lett (2015) 25 : 5682 -5686
PubMed 26564266 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.85 7.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL20210 RUPINTRIVIR 2.0 1 7.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL20210 RUPINTRIVIR EC50 = 14.0 nM 7.85