Assay Detail
Binding
CHEMBL3744097
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Binding affinity to adenosine A2A receptor (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
New substituted 9-propyladenine derivatives as A2Aadenosine receptor antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.70 | 8.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3087715 | — | — | 1 | 8.43 |
| CHEMBL576447 | — | — | 1 | 6.82 |
| CHEMBL567012 | — | — | 1 | 5.87 |
| CHEMBL304009 | — | — | 1 | 5.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3087715 | — | Ki | = | 3.7 | nM | 8.43 |
| CHEMBL576447 | — | Ki | = | 150.0 | nM | 6.82 |
| CHEMBL567012 | — | Ki | = | 1340.0 | nM | 5.87 |
| CHEMBL304009 | — | Ki | = | 2200.0 | nM | 5.66 |