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Assay Detail

CHEMBL3744100

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to adenosine A3 receptor (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Transmembrane domain-containing protein TMIGD3 (CHEMBL3712907)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

New substituted 9-propyladenine derivatives as A2Aadenosine receptor antagonists
Lambertucci C, Buccioni M, Dal Ben D, Kachler S, Marucci G, Spinaci A, Thomas A, Klotz K, Volpini R
Medchemcomm (2015) 6 : 963 -970
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.24 5.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL576447 1 5.50
CHEMBL567012 1 4.97

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL576447 Ki = 3200.0 nM 5.50
CHEMBL567012 Ki = 10800.0 nM 4.97