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Assay Detail

CHEMBL3748090

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Norovirus RNA dependent RNA polymerase by spectrophotometry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Norovirus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Recent Advances in the Discovery of Norovirus Therapeutics.
Kim Y, Galasiti Kankanamalage AC, Chang KO, Groutas WC.
J Med Chem (2015) 58 : 9438 -9450
PubMed 26258852 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 7.56 7.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL413376 SURAMIN HEXASODIUM 3.0 1 7.57
CHEMBL3746109 1 7.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL413376 SURAMIN HEXASODIUM EC50 = 27.0 nM 7.57
CHEMBL3746109 EC50 = 28.0 nM 7.55