Assay Detail
Functional
CHEMBL3748328
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Cytotoxicity against human DU145 cells by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of novel lipoamino acid derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.94 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.22 |
| CHEMBL3747292 | — | — | 1 | 4.72 |
| CHEMBL3746340 | — | — | 1 | 4.51 |
| CHEMBL3746346 | — | — | 1 | 4.31 |
| CHEMBL3747025 | — | — | 1 | - |
| CHEMBL3746616 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL3747292 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL3746340 | — | IC50 | = | 30800.0 | nM | 4.51 |
| CHEMBL3746346 | — | IC50 | = | 49100.0 | nM | 4.31 |
| CHEMBL3747025 | — | IC50 | = | 154400.0 | nM | - |
| CHEMBL3746616 | — | IC50 | = | 214900.0 | nM | - |