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Assay Detail

CHEMBL3749034

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Inhibition of aeromonas proteolytica aminopeptidase using L-leucine-p-nitroanilide as substrate by spectrophotometry
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Vibrio proteolyticus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

Development of a novel sulfonate ester-based prodrug strategy.
Hanaya K, Yoshioka S, Ariyasu S, Aoki S, Shoji M, Sugai T.
Bioorg Med Chem Lett (2016) 26 : 545 -550
PubMed 26642767 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 6.72 6.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL225164 CLOXYQUIN 2.0 1 6.72
CHEMBL3746376 1 -
CHEMBL3747198 1 -
CHEMBL3747278 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL225164 CLOXYQUIN Ki = 190.0 nM 6.72
CHEMBL3746376 Ki > 100000.0 nM -
CHEMBL3747198 Ki > 100000.0 nM -
CHEMBL3747278 Ki > 100000.0 nM -