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Assay Detail

CHEMBL3750533

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Binding
Binding affinity to NPY1R in human MCF7 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type MCF7
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Neuropeptide Y receptor type 1 (CHEMBL4777)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

N(ω)-Carbamoylation of the Argininamide Moiety: An Avenue to Insurmountable NPY Y1 Receptor Antagonists and a Radiolabeled Selective High-Affinity Molecular Tool ([(3)H]UR-MK299) with Extended Residence Time.
Keller M, Weiss S, Hutzler C, Kuhn KK, Mollereau C, Dukorn S, Schindler L, Bernhardt G, König B, Buschauer A.
J Med Chem (2015) 58 : 8834 -8849
PubMed 26466164 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 10.13 10.13

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3747715 1 10.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3747715 Kd = 0.074 nM 10.13