Assay Detail
Functional
CHEMBL3756271
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth inhibition of human Calu6 cells carrying a wild-type B-Raf
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Calu-6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of EBI-907: A highly potent and orally active B-Raf(V600E) inhibitor for the treatment of melanoma and associated cancers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.34 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3751896 | — | — | 1 | 6.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3751896 | — | IC50 | = | 455.0 | nM | 6.34 |