Assay Detail
Binding
CHEMBL3756277
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Binding affinity to 5-HT 1D (unknown origin) by competition binding assay
13
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Receptor binding profiles and quantitative structure-affinity relationships of some 5-substituted-N,N-diallyltryptamines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 13 | 6.58 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2391541 | — | — | 3 | 7.00 |
| CHEMBL3754166 | — | — | 2 | 6.90 |
| CHEMBL3752900 | — | — | 2 | 6.67 |
| CHEMBL3753318 | — | — | 2 | 6.40 |
| CHEMBL3752576 | — | — | 2 | 6.16 |
| CHEMBL3754496 | — | — | 2 | 6.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2391541 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL3754166 | — | Ki | = | 125.89 | nM | 6.90 |
| CHEMBL2391541 | — | Ki | = | 150.0 | nM | 6.82 |
| CHEMBL3752900 | — | Ki | = | 213.8 | nM | 6.67 |
| CHEMBL3753318 | — | Ki | = | 398.11 | nM | 6.40 |
| CHEMBL3752576 | — | Ki | = | 691.83 | nM | 6.16 |
| CHEMBL3754496 | — | Ki | = | 758.58 | nM | 6.12 |
| CHEMBL3754496 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL3752900 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL3752576 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL3754166 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL3753318 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL2391541 | — | Ki | < | 10000.0 | nM | - |