Assay Detail
Functional
CHEMBL3756431
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Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | BV-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Total Syntheses and Biological Evaluation of (±)-Botryosphaeridione, (±)-Pleodendione, 4-epi-Periconianone B, and Analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.63 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3751873 | — | — | 1 | 6.82 |
| CHEMBL3753054 | — | — | 1 | 6.64 |
| CHEMBL3753914 | — | — | 1 | 6.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3751873 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL3753054 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL3753914 | — | IC50 | = | 380.0 | nM | 6.42 |