Assay Detail
Binding
CHEMBL3756488
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Binding affinity to alpha-2B adrenergic receptor (unknown origin) by competition binding assay
12
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Receptor binding profiles and quantitative structure-affinity relationships of some 5-substituted-N,N-diallyltryptamines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 12 | 6.52 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3752900 | — | — | 2 | 6.77 |
| CHEMBL3754496 | — | — | 2 | 6.66 |
| CHEMBL3754166 | — | — | 2 | 6.64 |
| CHEMBL3752576 | — | — | 2 | 6.52 |
| CHEMBL3753318 | — | — | 2 | 6.36 |
| CHEMBL2391541 | — | — | 2 | 6.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3752900 | — | Ki | = | 169.82 | nM | 6.77 |
| CHEMBL3754496 | — | Ki | = | 218.78 | nM | 6.66 |
| CHEMBL3754166 | — | Ki | = | 229.09 | nM | 6.64 |
| CHEMBL3752576 | — | Ki | = | 302.0 | nM | 6.52 |
| CHEMBL3753318 | — | Ki | = | 436.52 | nM | 6.36 |
| CHEMBL2391541 | — | Ki | = | 724.44 | nM | 6.14 |
| CHEMBL3754496 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL3752900 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL3754166 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL3753318 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL2391541 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL3752576 | — | Ki | < | 10000.0 | nM | - |