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Assay Detail

CHEMBL3756528

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HCV GST-tagged recombinant NS3/4A protease expressed in Escherichia coli by microfluidic affinity assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Hepatitis C virus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates.
Cannalire R, Barreca ML, Manfroni G, Cecchetti V.
J Med Chem (2016) 59 : 16 -41
PubMed 26241789 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.62 7.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1407943 CLEMIZOLE 2.0 1 7.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1407943 CLEMIZOLE IC50 = 24.0 nM 7.62