Compound Detail
CHEMBL1407943
CLEMIZOLE 🧪 Phase II
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL1407943 |
| Name | CLEMIZOLE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | CJXAEXPPLWQRFR-UHFFFAOYSA-N |
7
Targets
9
Activities
2
Assay Types
0
PK Parameters
20
Publications
4
Known Names
3
Indications
Molecular Properties
325.8
MW (Da)
4.33
ALogP
3
HBA
0
HBD
21.1
PSA (Ų)
0.71
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Indications
Carcinoma, Hepatocellular Lennox Gastaut Syndrome Hepatitis C
Activity Summary
IC50 6 meas. best 7.62
EC50 3 meas. best 5.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 7.62 | 7.62 | 24.0 | 1 |
| Short transient receptor potential channel 5 CHEMBL4523481 | IC50 | 5.96 | 5.96 | 1100.0 | 1 |
| Short transient receptor potential channel 4 CHEMBL1741219 | IC50 | 5.19 | 5.19 | 6400.0 | 1 |
| Hepatitis C virus CHEMBL379 | EC50 | 5.1 | 4.9467 | 8000.0 | 3 |
| Short transient receptor potential channel 3 CHEMBL2417348 | IC50 | 5.04 | 5.04 | 9100.0 | 1 |
| Short transient receptor potential channel 6 CHEMBL2417347 | IC50 | 4.95 | 4.95 | 11300.0 | 1 |
| Short transient receptor potential channel 7 CHEMBL4523502 | IC50 | 4.58 | 4.58 | 26500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine