Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL4523481 Target Snapshot

Short transient receptor potential channel 5 · SINGLE PROTEIN · Mus musculus

53Compounds
5Assays
0Approved Drugs
20.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9QX29. Use UniProt Q9QX29 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9QX29 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Short transient receptor potential channel 5 as ChEMBL target CHEMBL4523481, mapped to UniProt Q9QX29. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Short transient receptor potential channel 5
SINGLE PROTEIN · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL4523481
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9QX29
Short transient receptor potential channel 5
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Short transient receptor potential channel 5 is the right protein anchor across sources, using UniProt Q9QX29 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelShort transient receptor potential channel 5
UniProt AccessionQ9QX29
Component TypeProtein
Sequence Length975 aa

Short transient receptor potential channel 5

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Short transient receptor potential channel 5, mapped to UniProt Q9QX29. Sequence length is 975 aa.

Mapped IDQ9QX29
Review nameShort transient receptor potential channel 5
OrganismMus musculus
Clinical Profile

Clinical Phase Distribution

1
Phase II
Assay Mix

Activity Type Distribution

IC5020.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1407943 5.96 IC50 1100.0 Clinical
CHEMBL4442673 5.74 IC50 1820.0 Preclinical
CHEMBL4436705 5.51 IC50 3100.0 Preclinical
CHEMBL2396913 5.46 IC50 3500.0 Preclinical
CHEMBL1345058 5.39 IC50 4060.0 Preclinical
CHEMBL4438892 5.35 IC50 4440.0 Preclinical
CHEMBL4467732 5.32 IC50 4800.0 Preclinical
CHEMBL4454505 5.2 IC50 6260.0 Preclinical
CHEMBL4438838 5.18 IC50 6600.0 Preclinical
CHEMBL4540486 5.16 IC50 6930.0 Preclinical
Distribution

pChEMBL Value Distribution

10
5.0
3
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

5
Total Assays
19
Tested Compounds
1
Assay Types
Binding — 5 assays, 19 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 4 19 5.2
single protein format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine